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Specifically, acute and chronic prolonged wakefulness in mice induced by modafinil treatment produced LTP of glutamatergic synapses on hypocretin/orexin neurons in the lateral hypothalamus, a well-established arousal/wake-promoting center

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Psoriasis patients were found to have increased amounts of LL-37 in their skin lesions, and it appears to promote inflammation by activating plasmacytoid dendritic cells and inducing an autoimmune response-like process

[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Randle P
