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Loop 3 provides the necessary flexibility in the ABS of the bacterial GUSs to accommodate various substrates According to the enzyme-activity analysis, all GUSs accepted one or more substrates larger than 10 , but the superimpositions of Cp GUS and Rg GUS with the Bifd GUS E479A / 10 complex indicated possible steric clashes between the aglycone and loop 5 or loop 3 of Cp GUS and Rg GUS, respectively

Multi-scale characterization of tumor-draining lymph nodes in resectable lung cancer treated with neoadjuvant immune checkpoint inhibitors

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The druglike and orally bioavailable compounds identified herein are active in animal models of schistosomiasis with a broader range of developmental stages targeted than the drug of choice, PZQ

[DOI] [PubMed] [Google Scholar] 161.Sato M., Kusumi R., Hamashima S., Kobayashi S., Sasaki S., Komiyama Y., Izumikawa T., Conrad M., Bannai S., Sato H

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