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Radiological diagnosis of an IMS is difficult and affected by tumor characteristics such as melanotic pigment concentration, hemorrhagic state, and differences in contrast uptake

In some cases, this pathology may lead to the development of hypothyroidism [1,2]

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Important aspects like fibroblast heterogeneity, functional specialization and cellular plasticity are also discussed as well as the implications that these aspects may have in disease and in the design of novel therapeutics

[DOI] [PubMed] [Google Scholar] 196.Ringseis R, Ldi S, Hirche F, Eder K