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We concentrated on providing novel findings on previously unidentified mechanisms of ASD treatment

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Evidence in support of this interpretation is provided by the occurrence of somatic second hit mutation or loss of heterozygosity at the NF1 locus that may influence the severity of the disease [260]

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To test the hypothesis that a disorder of ROS homeostasis is induced by OsG-produced oxidative stress, an antioxidant, GSH (50 mg/kg/ 6 h), was subcutaneously injected into animals with LOsG challenge as described above, defined as the LOsG.TdGSH group ( n = 10)
