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Recent studies have demonstrated that adipocyte iron content can influence lipid handling through fat-gut crosstalk (22), while macrophage iron loading in adipose tissue affects inflammatory responses and metabolic deterioration (40)
Outcome 00:14:31 Meta-analysis, Methods, Evidence Quality 00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data 00:33:53 Sponsor: AG1 00:35:05 Dont Turn Your Brain Off
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The mitochondrial transcription factor A (TFAM) mRNA carried by MSC-EVs can alleviate mitochondrial damage and inflammation by stabilizing mtDNA (Zhao et al., 2021)
[DOI] [PubMed] [Google Scholar] 130.Kotaja N
Therapeutic options remain severely limited
