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Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): A randomised, open-label, phase 3 trial

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However, it appears that these risks are reduced in younger women and when HRT is used soon after menopause (in other words, the risks are higher in older women and when HRT is used longer after menopause)