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5 Impact and mechanism of local anesthetics on mitochondria Local anesthetics such as lidocaine, bupivacaine, and ropivacaine block sodium ion channels on nerve fibers, inhibiting pain signal transmission, reduce general anesthesia requirements during surgery, and assist in postoperative pain management

10.1016/j.cell.2017.07.042 314 SatoS.BasseA

Combining these findings with clinical experience and data from case series which suggested possible efficacy re-treatment with immunoglobulin in GBS led to consideration of the possibility that some individuals may have a quicker IgG clearance and hence require higher dose or repeat treatment, to achieve a potentially improved outcome

Sacks F, Tonkin A, Craven T, Pfeffer M, Shepherd J, Keech A, Furberg C, Braunwald E

The cellular and organismal effects of nitroxides and nitroxide-containing nanoparticles
