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Glutathione synthesis is regulated mainly by the availability of precursor cysteine and the concentration of glutathione itself which feeds back to regulate its own synthesis

2015;308:L587L602

LKB1 inactivation has recently been reported to drive tumor progression by cooperating with certain activating oncogene mutations in various models of cancer (239242)

10.1016/j.ajpath.2020.03.007 110 SaechanC.NguyenU

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