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Serotonin is in turn a precursor for melatonin, a hormone involved in sleep regulation and synthesized mainly in the pineal gland

Mostofa and Fujita, 2013

Indeed, superoxide can undergo dismutation to H 2 O 2 , a mild oxidant that can be converted to the highly reactive hydroxyl radical in the presence of transition metals (Fe 2 + , Cu + ) by means of the Fenton reaction

IUPHAR-GI section symposium, Honolulu, Hawaii, 2002, 1315 July, O32

The proteoglycan and water content of the discs reduces with aging and injury

[DOI] [PMC free article] [PubMed] [Google Scholar] Huang P., Chen Y., Lin H., Yu L., Zhang L., Wang L., Zhu Y., Shi J