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N Engl J Med 376:25562565 Wu Q, Rayman MP, Lv H et al (2015) Low population selenium status is associated with increased prevalence of thyroid disease

PMID: 33057207

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In medicine, derivatives of EDTA are used for chelation therapy to bind and remove harmful metal ions

Mol Cell 40:893904 Tashkandi HM, Althagafy HS, Jaber FA, Alamri T, Al-Abbas NS, Shaer NA, Harakeh S, Hassanein EH (2023) Vinpocetine mitigates methotrexate-induced duodenal intoxication by modulating NF-B, JAK1/STAT-3, and RIPK1/RIPK3/MLKL signals

However, thyroid peroxidase (TPO)Ab levels significantly decreased after treatment with vitamin C and remained constant in placebo, emphasising the antioxidant benefit of vitamin C on antibodies specific to the thyroid