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Measures should be taken to ensure that the transplanted cells thrive within the hostile environment of a degenerating IVD by directly contributing to ECM synthesis and inducing a reparative shift in native cell activity via paracrine signaling or by facilitating the arrival of regenerative cells and preventing the infiltration of harmful cells

Estimation of Ascorbate Peroxidase (APX)(EC 1.11.1.1) Estimation of APX was done by following the method of Nakano and Asada (1981)
