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Because they work only where their matching tissue sequences are recognized, they minimize effects on non-target tissues

Avicenna J Med Biotechnol 8:1622 Shevchik VE, Condemine G, Robert-Baudouy J (1994) Characterization of DsbC, a periplasmic protein of Erwinia chrysanthemi and Escherichia coli with disulfide isomerase activity

Pedro, A

[24] In addition, the formation of new spines may not significantly contribute to the connectivity of the brain, and spine formation may not bear as much of an influence on memory retention as other properties of structural plasticity, such as the increase in size of spine heads

Cell Motil Cytoskeleton 1994

It is important to note that, since death signaling is not confined to the SN and its related areas, similar signaling may also occur throughout the brain in PD patients and models