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Neuroimaging studies have shown a reduction in hippocampal volume and abnormal prefrontal cortical activity, which strongly correlates with impairments in verbal memory and information processing speed ( 2.3.2 Psychiatric symptoms METH abuse disrupts the functionality of various brain regions, including the prefrontal cortex, nucleus accumbens, and thalamus, leading to significant psychiatric disturbances (Sekine et al., 2001)
References 1.Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L

Among various TRP channels, the transient receptor potential melastatin 8 (TRPM8) and transient receptor potential vanilloid 1 (TRPV1) are dominantly expressed in sensory neurons of the cornea and conjunctiva [22,23,24]

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News Release February 24, 2018 Magnesium, Curcumin, and Apple Cider Vinegar Rise in Popularity, While Probiotics Dip and Calcium Continues to Decline in Latest ConsumerLab.com Survey of Supplement Users White Plains, New York, February 24, 2018 A recent survey of 11,446 people who use dietary supplements shows that magnesium and curcumin and turmeric have leapt into the top 5 most popular dietary supplements, just behind vitamin D, fish oil and CoQ10
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