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Quantified by electron spin resonance (ESR), the scaffold scavenged 70% of hydroxyl radicals within 6 h, potentially disrupting ROS/NF-B-driven inflammatory feedback loops [45]

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Long term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls

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119 In short, SLC7A11 is an important target for the treatment of cancer and more and more SLC7A11 inhibitors have been discovered and reported

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10.1038/s41577-021-00506-1 21

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Deletion of TAK1 specifically in intestinal epithelial cells leads to a decrease in the protein levels of NRF-2 in the intestine

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