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Differentiation markers, such as Sycp3, Dmc1 , Rec8 , and Transition proteins 1 ( TP1) also exhibited a significant decreasing trend (Fig

[DOI] [PubMed] [Google Scholar] 35.Silveira J.S., Antunes G.L., Kaiber D.B., da Costa M.S., Marques E.P., Ferreira F.S., Gassen R.B., Breda R.V., Wyse A.T.S., Pitrez P., et al

Early cellular homeostasis in AD involves mitochondrial damage, and cell ROS levels result in abnormal mitophagy and autophagy

Cox HD, et al

[DOI] [PubMed] [Google Scholar] 13.Khrle J

Third, and perhaps most relevant, it promotes fibroblast migration and collagen synthesis , the exact cellular processes needed to rebuild the damaged annulus fibrosus