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The Epworth Sleepiness Scale (ESS), Athens Insomnia Scale (AIS), and Pittsburg Sleep Quality Index (PSQI) were used to quantify excessive daytime sleepiness (EDS), insomnia symptoms, and sleep quality, respectively

NHS Guidelines on B12 Treatment and Weight Management The NHS follows NICE and British Society for Haematology guidelines for B12 deficiency management, which emphasise evidence-based diagnosis and treatment protocols

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Intramuscular vs Subcutaneous Parenteral administration of vitamin B-12 via injection has been standard protocol for decades, according to the Centers for Disease Control and Prevention

Improve Stress Levels: The stress hormone cortisol has been proven to be decreased by vitamin B12, which has been shown to assist in controlling the body's reaction to stress

A study using C57BL/6J mice concluded that B12 supplementation minimally impacts microbial community structure under healthy conditions but does after DSS-induced colitis treatment [46]
