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Upon administration, ADG206 is selectively activated within the tumor microenvironment, targeting and activating CD137 on various leukocyte subsets, including activated T lymphocytes and NK cells [38]

This ingredient is intended for use in extemporaneous compounding only

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Reda A, Veys K, Kadam P, Taranta A, Rega LR, Goffredo BM, Camps C, Besouw M, Cyr D, Albersen M, Spiessens C, de Wever L, Hamer R, Janssen MCH, DHauwers K, Wetzels A, Monnens L, van den Heuvel L, Goossens E, Levtchenko E (2021) Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis

doi: 10.1136/gut.48.1.28

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