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208 In 2016, the pyrazole compound 8 (APX-115 also known as Ewha-18278) was reported as a pan-NOX inhibitor ( K i of 1.08, 0.57, and 0.63 M for NOX1, NOX2, and NOX4, respectively) with no activity on xanthine oxidase or glucose oxidase
Despite extensive research highlighting their neuroprotective, antioxidant, anti-inflammatory, antibacterial, dermatological, antitumor, and antidiabetic properties, the underlying mechanisms remain only partially understood
Do you require an organic chemistry degree to unravel the science behind these compounds and understand their benefits
33 NatarajB
Acta 1867 , 8287 (2019)
10.4161/cc.7.24.7231
