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5-Amino-1MQ is an orally bioavailable, cell-permeable small molecule that potently inhibits NNMT (nicotinamide N-methyltransferase), the enzyme responsible for methylating nicotinamide to 1-methylnicotinamide (1-MNA)

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[DOI] [PubMed] [Google Scholar] 180.Sohn J, Rudolph J

To accomplish this, we have undertaken phenotypic profiling and gene expression analysis in these mutant strains

H., Lombard L