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Addressing these limitations, future preclinical studies should prioritize longitudinal designs with nAChR subtype-specific agonists/antagonists and genetically engineered models incorporating humanized nAChR subunits

For DNA compaction analysis, the maxima of foci detection were used as described previously 20

Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders

Associations between plasma growth and differentiation factor-15 with aging phenotypes in muscle, adipose tissue, and bone

Overall, the recovery journey varies by person but trends toward better resilience

The anti-inflammatory effects of melatonin occur by inhibiting the transcription factors involved in generating pro-inflammatory cytokines (e.g., activator protein 1, hypoxia-inducible factor-1, nuclear factor erythroid 2 factor 2, and nuclear factor kappa B), prostaglandin synthesis, reduced the production of adhesion molecules, neutrophil infiltration into tissues, and COX-2 (cyclooxygenase-2) levels