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2.2 Repolarizing tumor-associated macrophages with peptides Tumor-associated macrophages (TAMs) play a central role within the TME, and their reprogramming is intricately linked to the transformation of this environment (Xiang et al., 2021)

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5-Amino-1MQ's mechanism centers on NNMT inhibition: NNMT inhibition : Selectively blocks NNMT with an IC50 of approximately 1.2 microM
