bpc-157 research human safety and the Difference Between an Evidence Gap and a Cover-Up: What the entire evidence base actually looks like, and the questions to ask next. — WellFounded BPC-157 for athletes and injury
Description
In a study of patients with chronic low back pain, Vitamin B12 given for 2 weeks reduced pain by 32% compared to placebo [Chiu, 2011] In a 2020 systematic review looking at the use of B12 for nerve-related pain it was found that there is moderate evidence for the therapeutic effect of B12 in the treatment painful peripheral neuropathy [Julian, 2020]

Research protocols typically use 250 to 500 mcg administered subcutaneously once or twice daily for 4 to 8 weeks

Simultaneously, they arent absorbing vitamin B12 well because of changes to their digestive tract

Denominator evidence: Frey C, et al
Methotrexate injectable solution can cause drowsiness

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