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Overall, no clear benefit on ventricular function has been demonstrated, but some trials have found coenzyme Q 10 supplementation improved exercise capacity and reduced mortality

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Winther SA, llgaard JC, Hansen TW, von Scholten BJ, Reinhard H, Ahluwalia TS, et al

Isoniazid (for tuberculosis) may reduce vitamin B6 levels and raise nerve-damage risk

As the disease progresses however it becomes increasingly non-responsive to therapeutic interventions [92,93]
