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Cell (2017) 10.1016/j.cell.2017.02.031 The seminal paper demonstrating FOXO4-DRI's mechanism and efficacy

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It matters because a small molecule behaves differently from a peptide in dosing, stability, and how it is studied

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
CC performed the primary data analysis, and FV and KR performed secondary data analyses

It is a key distinction from growth hormone secretagogues or GHRH analogues that require functional pituitaries to work
