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Description
Ferroptosis is driven by lipid peroxidation, relying on Fe 2+ -mediated Fenton reactions, and occurs in close association with dysregulation of the SLC7A11/GSH/GPX4 antioxidant system

Morbidity and mortality in patients with rheumatoid arthritis compared with an age- and sex-matched control population: A nationwide register study

Interestingly, loss of FH also triggered a compensatory rise in GSH levels by upregulation of cystine transport SLC7A11 expression and increases in cystine uptake and glutaminolysis-dependent GSH biosynthesis (121)

Cell Rep 39:110860 Sol C, Nadal-Ribelles M, Kraft C, Peter M, Posas F, de Nadal E (2011) Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress

This study has several strengths

After an eye exam 7 years ago, my eye doctor told me I had the start of cataracts
