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Endoplasmic Reticulum Transport of Glutathione by Sec61 Is Regulated by Ero1 and Bip

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Glycolate then is transferred to the peroxisomes where it is converted back to glyoxylate and the resulting glyoxylate, along with alanine, serve as substrates, for the AGXT encoded enzyme (see Figure below) which releases glycine and pyruvate

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The control tubes contained equal amounts of 0.2 M NaOH without Nitisinone

Figure 5 Metabolomics analysis Differential metabolites are listed in Table 1 and Supplementary Table 1