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Figure 1 2.1.2 Functional aspects of the gut microbiota The gut microbiota is integral to numerous metabolic and nutritional processes that facilitate digestion

On the other hand, genetic overexpression of CBS in the brain caused dysregulation of serotonin and dopamine pathways [167] and contributed to Down syndrome-associated neuronal disturbances [168]

Moreover, exhausted T cells are enriched in tumor-reactive clones [217, 218]

Peptides support immune system function by promoting the production and activity of immune cells, improving cellular repair, and reducing inflammation

In accordance, in an investigation that was conducted on 11 insulinoma patients and 18 healthy individuals to assess the amounts of insulin, proinsulin, C-peptide, glucose of plasma, and -hydroxybutyrate after a prolonged fast, it was revealed that conventional reference values of insulin are not applicable while using specific immunoassay such as enzyme-linked immunosorbent assays (ELISA) [76]

Atherosclerosis is a primary factor in cardiovascular diseases, characterized by the hardening and narrowing of arteries