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TOKOFF-RUBIN, N.E

C.TanX.LiW

Parallel advances in clinical trial design, such as Bayesian and adaptive models, are also expected to improve patient stratification, accelerate recruitment, and optimize dosing regimens, ultimately increasing the efficiency of drug development pipelines 91

Among the metabolic alterations induced by cystine deprivation, one often neglected consequence is the aberrant accumulation of intracellular glutamate due to the lack of extracellular cystine as exchange molecules for sustained system x C - activity

Due to their strong dd transitions, MnO nanostructures are commonly applied as quenchers in turn-off/on fluorescence probes [69]

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