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GHRP-2 is generally considered stronger or more stimulating in some contexts, but it is also more closely associated with ghrelin-like appetite effects and broader endocrine activity

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Experiments performed in differentiated SH-SY5Y neuroblastoma cells have shown that exposure to PS-NPs downregulates expression of the CI subunit NDUFB8, leading to diminished basal and maximal oxygen consumption rates alongside increased proton leakagefurther confirming mitochondrial CI dysfunction 32

It therefore plays a role in the regulation of fat and sugar metabolism

10.1097/SHK.0000000000001751 49 MaS.SunL.WuW.WuJ.SunZ.RenJ

Figure 7 Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author