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Adicionalmente, contribuye a la activacin de las vas de sealizacin intracelular dependientes de PI3K/Akt y MAPK/ERK, que median los efectos del NGF sobre la supervivencia neuronal y el crecimiento axonal

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It has previously been suggested that the GT II assay is able to reliably detect mixed infections if the minor genotype/subtype represents at least 2030% of the circulating variants (similarly to Sanger sequencing) 13,35

The rationale behind this approach lies in the understanding that chronic inflammation plays a pivotal role in the pathophysiology of varicocele, leading to oxidative stress and subsequent impairment of spermatogenesis and erectile function