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In summary, nutritional ketosis may serve as a cardioprotective alternative energy supply in the failing heart and reduce pathological ventricular remodeling and could serve as a supportive, non-pharmacologic treatment in people with heart failure along current treatments, such as SGLT2 inhibitors (103, 104)

Most patients in the treatment group shifted from grade 2 or 3 to grade 0 or 1, which is defined as clear or almost clear as assessed by IGA scoring (Figure 2(d))