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Immature T cells, known as thymocytes, undergo the process of selection and differentiation under the influence of thymosins

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Less than 15% reaches systemic circulation due to first-pass hepatic metabolism and gastric acid degradation

While the majority of gastric enteric neurons receive vagal innervation, there is only a relatively minor contribution of vagal efferent inputs to the distal intestine and colon, both structurally and functionally [10]

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