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First annual Michigan Spine Society Meeting

Mechanistically, propofol enhances -aminobutyric acid (GABA) receptor activity, maintaining neurons in their resting state, while Dex, a selective 2 -adrenergic receptor agonist, primarily affects the locus coeruleus, resulting in effects resembling natural sleep

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Oncogene 33 (21), 27092716 (2014)
2001 Feb;34(2):137-51 126
Another example of redox regulation of insulin receptors has been shown for IGFs