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GHK-Cu then works on the other side of the equation activating Wnt/beta-catenin, reducing DHT receptor sensitivity, and providing anti-inflammatory support

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Betaine synergistically enhances obesity and its metabolic complications through various targets via the AMPK-mitochondrial axis, SIRT1/SREBP-1/PPAR signaling, inhibition of inflammation, and the microbiota-SCFA-epigenetic cascade, providing a mechanistic basis for its clinical translation

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