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Initial intensive regimens are followed by maintenance schedules

It was found that lignan, 3,3-bisdemethylpinoresinol exhibited potent inhibition of intracellular MMP-1 expression in UVA-irradiated normal human dermal fibroblasts

A.SteinbergM

(1978b)

Indeed, the fact that vitamin E is lipid soluble means that supplementation with megadoses of vitamin E can result in large increases in body stores of this vitamin