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During the catagen and telogen phases, follicle regression and quiescence are regulated by apoptotic molecules (such as Bax, Fas) and cell cycle inhibitors (such as p21, p27)

The consensus among experts is that the majority of studies performed on humans are focused on topical application

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10.1089/ars.2013.5302 36 Nianiou-ObeidatI.MadesisP.KissoudisC.Voulgari1G.ChronopoulouE.TsaftarisA.et al (2017)

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This finding implies that plant tannins can effectively inhibit HBV replication in cells perhaps as a novel anti-hepatitis B virus drug providing new research ideas for the clinical treatment of HBV as well as other viral infectious diseases