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2 Therefore, there is an urgent need to further clarify the molecular mechanism of CRC tumorigenesis and pathogenesis

The results of the ECHELON-2 phase III trial for an A + CHP regimen demonstrated that the 5-year PFS rates and OS rates were significantly higher in the A + CHP group compared to the CHOP group (51.4% vs

The neurite length was also enhanced in the P301L cells, suggesting that mitochondrial transplantation improves the neurite elongation capacity of these cells

Central to the pathogenesis of MASH, hepatic lipid overload occurs with excessive uptake of fatty acids released from the adipose tissue, enhanced de novo lipogenesis from excessive carbohydrate intake or inhibition of fatty acid -oxidation (FAO) 3,4,5

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137,138 In the brain, LDH is critical for lactate metabolism, 139 and neurons use lactate released by astrocytes as an energy substrate