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Briefly, cell samples were collected and homogenized in TRIzol reagent on ice, or tissue samples were snap-frozen in liquid nitrogen and pulverized

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There was evidence that mice without efficient expression of SOD2 enzyme resulted in significant epidermal thinning. In humans mitochondrial dysfunction promotes cellular senescence in epidermal keratinocytes in culture. [7] This means because of senescence, there were fewer cells in the epidermis, causing it to be thinner

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Concurrently, developing artificial intelligence-based models to predict exercise efficacy, integrating biomarkers such as gut microbiota and circulating exosomes, will provide new paradigms for precision exercise medicine