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Plant alkaloids such as berberine carried out the inhibition of NADPH oxidase activity via reducing the mRNA expression of gp91phox in macrophages

The implication of genetic polymorphisms in SFTPA2, SFTPC, MUC5B as well as DSP ( encoding desmoplakin) as risk factors for pulmonary fibrosis suggest that the integrity of the barrier function is critically important in maintaining lung homeostasis (Fingerlin et al., 2013)