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Mitophagy promotes resistance by clearing damaged mitochondria, maintaining metabolic fitness, reducing oxidative stress, suppressing ferroptosis, and facilitating immune evasion

2006;136:1636s-40s

While we often think of melanin as a single thing, it actually comes in two primary forms that dictate the hues we see on our bodies

Mutations in MMAA , MMAB , and MUT (corresponding to cblA, cblB, and mut complementation groups) are associated with isolated methylmalonic aciduria, while mutations in MTRR and MTR (corresponding to cblE and cblG complementation groups) are associated with isolated homocystinuria

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