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These responses involve the coordinated upregulation of antioxidant genes, glutathione S-transferase (GST ), catalase (Cat), glutathione-peroxidase (GPxs), hemeoxygenase1 (HO-1) and peroxiredoxins (Prdxs), to lessen the oxidative load and restore cellular homeostasis

DPP-4i plays an anti-apoptotic role by regulating the mitogen-activated protein kinase (MAPK)/ERK, phosphatidylinositol-3-kinase (PI3K)/AKT and NF-B signaling pathways

Ray B, Bisht S, Maitra A, Maitra A, Lahiri DK (2011) Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurc) in the neuronal cell culture and animal model: implications for Alzheimers disease

Entomol Gen 39(34): 221230 Zhao JZ, Collins HL, Li YX, Mau RFL, Shelton AM (2006) Monitoring of diamondback moth (Lepidoptera: Plutellidae) resistance to Spinosad, Indoxacarb, and Emamectin Benzoate

For the PANSS-N outcome, data were pooled from just 3 RCTs: those by Berk et al, 8 Breier et al, 9 and Conus et al

Furthermore, cognitive therapy is a direct active and systematically structured approach for the treatment of depression