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Description
Though considered rare, some people have reported anaphylactic responses
Genetically controlled membrane synthesis in liposomes
HMGB1, a typical DAMP, is an endogenous mediator of inflammation that can be released through apoptosis, ferroptosis, and necrosis (217)
The first reaction is catalyzed by tryptophan hydroxylase (TPH-1), which requires L-tryptophan, tetrahydrobiopterin (BH4), and O 2 as co-substrates, and has ferrous ion (Fe 2+ ) as an activator
Nature 389 , 294296 (1997)
doi: 10.1038/s41551-017-0119-4
