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Finally, genetic counselling can be proposed to families of an affected patient

Supports mitochondrial function and energy production

This study reported that the increased G protein-coupled receptor levels in Rett syndrome can be upregulated by CBDV, which could be a novel therapeutic target in future (276)

[56] [57] Additionally effective ideal non-gene editing and chemical-drug methods involve hypocretin treatments methods such as future drugs like hypocretin agonists (such as danavorexton) [58] or hypocretin replacement, in the form of hypocretin 1 given intravenous (injected into the veins), intracisternal (direct injection into the brain), and intranasal (sprayed through the nose), the latter being low in efficacy, at the low amount used in current experiments but may be effective at very high doses in the future

Mestre-Farrera A, Bruch-Oms M, Pea R, et al