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4-PBA is a small-molecule chemical chaperone that improves protein folding capacity, reducing ER stress

The epigenomic differences between germ-free and CNV mice had functional consequences on gastrointestinal health, confirmed by increased chromatin accessibility after induction of DSS colitis in genes playing a role in the inflammatory response of the colonic epithelium in CNV mice (166)

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Notably, RFC expression was not related to OS

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