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These include serious infection, uremia or renal failure, drugs with bone marrow suppression properties (e.g., chloramphenicol), or concurrent undiagnosed folic acid or iron deficiency anemia
Regular B12 screening is recommended, especially for those on Metformin for over four years
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BioMed Research International 2021:9924314
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The safety of this preparation in pregnancy and lactation has not been established
