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Epithelialmesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

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Cannabis is used in its unprocessed state as dried flower bulbs, known as marijuana, and as pieces of resin, known as hashish [12]

First-in-Human trials follow a cautious and progressive dose-escalation approach designed to support continuous safety evaluation throughout the study

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TMZ functions by methylating adenine and guanine at specific sites within the DNA sequence, resulting in the formation of three methylated products: N7-MeG, N3-MeA, and O6-meG