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The R118G mutation reduces the affinity of BioID for biotin and bioAMP (approximately 40-fold and 440-fold lower than that of the wild type, respectively), leading to a significant increase in the release of active bioAMP molecules
Acta Pharmacol
Demonstrated seven-fold greater blood-brain barrier penetration than BDNF (brain-derived neurotrophic factor) in rat hippocampal models
In total, we screen 63 genes in four metabolic states, corresponding to 2016 single and pair-wise genetic perturbations
Tumor Microenvironment Factors like hypoxia and acidity affect how cells use glutamine
