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Brain Res Bull 55: 327333
This nuclear presence of FOXO4 seems to be involved in maintaining the viability of senescent cells by possibly modulating downstream senescence-associated pathways, detailed by changes in p53, Ser15-phospho-p53, and p21 protein levels
Nedu, M.-E., et al
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Mechanistically, this results from compromised regulation of mitochondrial homeostasis by DJ-1
