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Five patients (1.9%) experienced a zoster (shingles) flare after the first dose but none after the second dose

1b) the highest prevalence is in West Berlin (up to 50%), Hamburg, and Bremen (Pommer et al., 1986)

10.1016/j.cell.2015.04.042 Summary Keywords intervertebral disc, low back pain, MSC, regenerative medicine, microenvironment, niche, extracellular vesicles (EVs), disc progenitor cells Citation Wang H, Xu A, Hua W, Mao J, Zhang J, Ma X and Lu L (2025) Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions

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