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Cells were either cultured in presence of 2-DG or not

AHK-Cu, by comparison, has been studied less extensively for skin applications
Nijhof IS, Casneuf T, van Velzen J, van Kessel B, Axel AE, Syed K, et al

Heres how it exerts its effects at the molecular level: 1

SAM consumption introduces a depletion of methyl donors, directly influencing global cellular methylation potential

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